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KMID : 0359920080270050631
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Korean Journal of Nephrology
2008 Volume.27 No. 5 p.631 ~ p.637
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A Case of Pneumocystis jirovecii Pneumonia Following CMV Duodenitis in a Kidney Transplant Patient
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Kim Hye-Won
Kim Hye-Ok
Cho Won-Yong
Kim Hyung-Kyu
Boo Chang-Su
Jo Sang-Kyung
Lee Kwang-Gyun
Kim Myung-Gyu
Woo Young-Seok
Oh Cho-Rong
Kim Ju-Hyung
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Abstract
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Solid organ transplant recipients are at increased risk for various opportunistic infections because of their immunocompromised state. Pneumocystis jirovecii (carinii) infection has posed serious problems in these patients which can be life threatening. It has been reported that incidences of Pneumocystis infection have dramatically decreased with the use of prophylactic antibiotics. However, there have been reports that say the risks of Pneumocystis infection are increasing with the use of new immunosuppressive drugs and in presence of preceding immunomodulating infections such as CMV infection which is another common opportunistic infection in transplant patients. There were only a few case reports abroad on Pneumocystis infection following CMV infection in patients who underwent kidney transplantation. In Korea, however, there hasnt been any report of such cases. Herein we report a case of a kidney transplant patient who experienced a serious episode of Pneumocystis jirovecii pneumonia following CMV duodenitis. After adequate mechanical ventilation and use of antibiotics the patient completely recovered without any complications.
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KEYWORD
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Kidney Transplantation, Pneumocystis, Cytomegalovirus
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